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Profhilo vs Dermal Fillers – Which is Right for You?
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Profhilo and dermal both contain acid, but they do completely different things. them — or them — is one of the most common we field at consultation. The short version: dermal fillers add and volume to places, while the overall hydration, elasticity, and quality of the skin itself.
This guide how each treatment works, where each one wins, and which to choose based on what you’re actually trying to fix.
The core difference in one paragraph
A dermal filler is a thicker, cross-linked acid gel. When injected, it stays where you put it — that’s the whole point. It lifts and contours, replacing volume in the cheeks, jawline, lips, tear trough, or chin. is a different animal: it’s a high-concentration, low-cross-linked acid that spreads after injection. It doesn’t lift or contour. Instead, it collagen and elastin across a broad area, improving skin firmness, hydration, and «glow» without changing facial shape.
If your face has lost volume — cheekbones, hollow temples, a heavier-looking — you need filler. If your face still has good structure but the skin itself looks dull, crepey, or dehydrated, you need . Plenty of patients in their late 30s and 40s need both.
How Profhilo works
Profhilo contains 64mg of hyaluronic acid in a 2ml syringe — one of the highest concentrations of any HA injectable on the UK market. Crucially, it uses a thermal to create hybrid complexes of high and low molecular weight acid, without chemical cross-linking agents. This matters traditional cross-linked fillers stay localised; Profhilo’s structure means it diffuses across the tissue plane after injection.
Once distributed, Profhilo four types of and production over the following weeks. The clinical effects — tighter, more hydrated, more luminous skin — build gradually over 4 to 8 weeks. There’s no immediate «before and after» the way there is with filler; is a slow burn.
The standard is two four weeks apart, with visible from around week 4 of the second treatment and 6 months before a session.
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How dermal fillers work
are cross-linked hyaluronic acid gels to hold their shape and stay in the anatomical layer where they’re placed. When injected deep on bone (cheekbones, chin, jawline), they restore structural support that has been lost to bone resorption and fat-pad . When more superficially (lips, tear trough, fine lines), they smooth and refine .
The result is immediate. You see the change as soon as you sit up. Hyaluronic acid is hygroscopic, so the filler continues to water over the following 2 weeks, with the final result visible at around 2 to 4 weeks post-treatment.
filler products have viscosities and lift capacities — the dense, structural products designed for deep cheek placement are entirely different from the soft, flowing products for lips. We choose based on site, not request.
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Where each treatment goes
treatment areas:
Dermal filler treatment areas:
The is small. doesn’t go in lips, tear troughs, or nose reshaping. Dermal fillers don’t go into broad sheets of skin for .
Treatment experience and downtime
Profhilo uses 10 standardised points across the lower face — 5 per side at landmarks chosen to maximise spread without compromising safety. The takes around 15 minutes. There’s no in Profhilo, so we apply topical cream first. You will see small raised bumps at each site after treatment; these disappear within 24 to 48 hours as the product . No in most cases, and you can return to work the same day.
Dermal fillers involve more variable technique — typically a combination of needles and cannulas, with multiple points depending on the area. Most filler products contain lidocaine, which numbs as it goes in. The takes 20 to 45 minutes on the number of areas . Some bruising and swelling is normal, particularly with lip filler, where swelling can last 3 to 7 days. Most are socially the next day; significant events should be at least 2 weeks out.
How long do the results last?
Profhilo results last 6 months from the second treatment. Maintenance is usually 1 to 2 per year depending on skin response and (sun exposure, smoking, and dehydration all longevity).
Dermal fillers last anywhere from 6 to 24 months depending on and placement. Lip fillers fastest (6 to 9 months); deep structural cheek and jawline filler lasts longest (18 to 24 months). Tear trough sits in the middle (9 to 12 months).
In direct cost terms, dermal are usually a longer-lasting investment per . In terms of treatment intent, they’re not really — they solve different problems.
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Cost comparison
At Centre for Surgery, Profhilo starts from £400 per session, with the full course of two sessions costing £750. Dermal fillers start from £400 for a 1ml lip treatment and scale with the volume of used — full cheek treatment is typically £900–£1,400 on volume; £1,200–£2,400; tear trough £450–£700.
Cost should not be the primary driver of which treatment you choose. The right question is what your face actually needs — and that’s a conversation, not a price .
Who is each treatment best for?
Profhilo is the right answer when:
Dermal are the right answer when:
Both at once when: you have both volume loss and skin quality — which is most patients over 40. We do Profhilo first, then layer in dermal fillers 2 to 4 weeks later, so we can assess each treatment’s effect independently.
What we don’t recommend
is not a for filler. If you have hollow cheeks or under-eye troughs, will not fix them. sometimes ask for Profhilo because it’s been marketed as «natural» or «non-invasive» — both treatments are non-invasive injectables, and both are made of acid. The question is whether you need volume or skin quality.
Equally, dermal filler is not a for Profhilo. more filler into a face that needs skin quality improvement makes the skin look worse, not better. We see patients who have been the wrong outcome with the wrong treatment for years.
We do not offer skin at all skin types or as a routine for — we do offer as a more option, particularly under the eyes, but it’s a and not directly comparable.
Other skin booster options
isn’t the only skin booster, though it’s the most clinically established. Other hyaluronic acid skin boosters use lower and different cross-linking strategies; results tend to be and more localised. We don’t use Teosyal Redensity 1 for routine skin work — its and protocol are different from Profhilo, and we focus on the with the evidence base for the outcomes our patients are looking for.
For the tear trough specifically, we use Teosyal 2, which is the only filler in our range specifically formulated for that anatomy. That’s a dermal filler, not a skin booster, and is a conversation from the Profhilo/filler .
Why choose Centre for Surgery?
We are a CQC-regulated clinic on Baker Street performing both and dermal filler treatments daily. All injectables are administered by . We carry hyalase for filler and events. Consultation is structured, written, and includes a 2-week cooling-off period before any .
Our for vs filler is to start with the question you actually want answered — what bothers you when you look in the mirror? — and work backwards to the that it. We won’t sell you Profhilo if what you need is filler, and we won’t sell you filler if what you need is .
To book a consultation, call , email , or complete the form below.
Centre for Surgery
Baker Street, London W1U 6RN
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Call or fill in the form below. A coordinator will call you within one working day to book your consultation with the best matched to your enquiry.
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Centre for Surgery is a CQC-regulated private on London’s Baker Street, delivering and surgery through specialist . Our expertise spans facial and , , for men, and body procedures such as and . Patient safety, surgical excellence and results sit at the heart of everything we do.
Centre for Surgery is a private on London’s iconic , offering plastic and cosmetic surgery led by consultant .
Marylebone
London
W1U 6RN
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Saturday available
